Man 'free' of HIV after stem cell treatment

Man 'free' of HIV after stem cell treatment

According to the research, which was published Monday in the journal Nature, nearly three years after receiving a stem-cell transplant from a donor who was genetically resistant to HIV, extensive testing shows that the man, whose identity was not revealed, has no detectable sign of the virus. Specifically, the donor had two copies of a version of the CCR5 gene.

He stopped taking ARTs soon after and 12 years later is still HIV-free, "in other words, he is cured".

The "London patient" who was infected with H.I.V. and suffered from Hodgkin's lymphoma, received a bone marrow transplant from a donor with the CCR 5 mutation in May 2016, the New York Times reported. The Guardina Newspaper in United Kingdom also reported that a London patient with HIV has become the second person ever to be free of the virus after a bone marrow transplant, raising hopes of a cure for Aids.

Fauci sees the report of the London patient as being less about the possible benefits of bone marrow transplants in treating or even curing HIV, and more about the need to focus HIV research on CCR5.

"Common to both approaches is the presence of a modified gene in our immune system (CCR5) that is necessary for HIV infection". Until now, Brown is the only person thought to have been cured of infection with HIV, the virus that causes AIDS.

The case was published online Monday by the journal Nature and will be presented at an HIV conference in Seattle.

The benefits of this treatment outweigh the risk for cancer patients, which is where it is most commonly used. Specifically, the donor had a mutation in a gene that codes for a protein called CCR5, which HIV uses as a "port" to get inside cells. Today people can live normal lives with HIV and, as best as we can tell, live to a full age.

The case is a proof of the concept that scientists will one day be able to end AIDS, his doctors said, but does not mean a cure for HIV has been found.

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Despite various attempts by scientists using the same approach, Brown had remained the only person cured of HIV until the new London patient.

Timothy Brown, the "Berlin patient," was given two transplants and underwent total body irradiation to treat leukemia, while the British patient received just one transplant and less intensive chemotherapy.

Possibly. The London patient's immune system is now created to block HIV's most common path into cells, using the CCR5 receptor.

This isn't a universal cure for HIV, but it's a pretty incredible development which indicates new avenues for research.

According to The Guardian, the patient who wishes to remain anonymous tested positive for HIV (human immunodeficiency virus) in 2003.

The only previous patient to be cured of the virus was Timothy Ray Brown, an American known as the "Berlin patient".

A new report surfaced saying a man who is HIV positive is now remission after receiving a bone-marrow transplant.

"I would like to meet the London Patient". "Everybody believed after the Berlin patient that you needed to almost die basically to cure HIV, but now maybe you don't".

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