New cancer-causing toxin found in recalled blood pressure pills

New cancer-causing toxin found in recalled blood pressure pills

The recall affects 25mg, 50mg, and 100mg tablets, according to a notice posted on the US Food and Drug Administration's website. NMBA had not been found in previously recalled ARB products, but the FDA continues its investigations.

Since 2018, there have been at least 19 recalls of versions of the drug over cancer fears. The contamination was found during heightened testing stirred by a far-reaching recall of generic blood-pressure drugs known as angiotensin II receptor blockers, or ARBs, that contain potential carcinogens NDMA and NDEA.

Camber Pharmaceuticals Inc. voluntarily recalled 87 lots of losartan tablets in the United States on Thursday.

"Our ongoing effort has determined that the impurities may be generated by specific chemical reactions in the manufacturing process of the drug's active pharmaceutical ingredients", said FDA Commissioner Scott Gottlieb, M.D., in a statement.

The medication is used to treat high blood pressure and congestive heart failure.

Problems with potential cancer-causing agents in blood-pressure medications first cropped up in July, when an ARB called valsartan was recalled by Chinese drugmaker Zhejiang Huahai Pharmaceutical Co. Ltd.

Mitchell claims first PGA win with big final putt
Koepka handled the treacherous Bear Trap as he birdied 16th and then his two-putt birdie on 18th took him past Palmer and Glover. Mitchell closed with a 3-under 67 to finish at 9-under 271 at PGA National, a stroke ahead of Brooks Koepka and Rickie Fowler .

Michael Bloomberg Won't Run For President
House of Representatives in congressional elections and has invested in advocating for sweeping gun-control laws. He said he believed change was more likely to occur outside Washington than by the Capitol and the White House.

Ex-NFL Player Accused of Lewd Contact With 77-year-old Woman
A third woman claims Winslow raped her when she was an unconsious 17-year-old at a San Diego party, when he was 19. The former National Football League player is back in jail once again for an accusation of sexual misconduct.

The remedy is packaged in 30 rely upon, 90 depend, 500 depend and 1000 rely on bottles.

The previous recalls of Losarta, Valsartan or Irbesartan involved too much N-Nitrosodiethylamine (NDEA) or N-nitrosodimethylamine (NDMA).

As the recalls have continued, the spotlight has shifted to overseas factories in China and India that now produce many drugs that end up in the US.

The FDA also said it is working to develop testing methods to detect other cancer-causing impurities.

You can find the list of lot numbers recalled by Camber Pharmaceuticals here.

And then there's Macleods Pharmaceuticals Limited, which announced on February 22, 2019, that it was initiating a recall on just one of its lots of Losartan tablets after traces of NDEA were detected by officials. "The FDA is committed to implementing measures to prevent the formation of these impurities during drug manufacturing processes in the future".

Related Articles