England's Billy Vunipola targeting Six Nations return

England's Billy Vunipola targeting Six Nations return

Young lock Nick Isiekwe has an ankle strain, while star second-rower Maro Itoje - who can also operate at flank - and hooker Jamie George had their noses broken in the 13-3 win in Glasgow on Sunday.

Billy Vunipola's latest setback only piles on the misery for England's talisman back-row forward, who missed the 2017 British and Irish Lions tour after shoulder surgery before serious knee trouble and two consecutive right-arm fractures denied him yet more Test match honours.

Mako Vunipola limped off with a calf strain and Nick Isiekwe is waiting to see a specialist after spraining his ankle on the artificial surface at Scotstoun.

"Mako has a calf injury but it's too soon to say what the extent of it is", he said.

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The injury comes not only as a huge blow to Saracens, but to England as well.

England will play South Africa (November 3), New Zealand (November 10), Japan (November 17) and Australia (November 24) in their autumn internationals, with each game exclusively live on Sky Sports.

Both brothers, who have been named in England's training squad for the forthcoming worldwide series, retreated to the bench, with Mako pictured with his leg in a protective brace and Billy with his arm packed in ice. Ben Morgan, unused since the 2015 Rugby World Cup, could become an option again. This time it is his left arm that has incurred the injury.

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